Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine–pyrimethamine is used to prevent malaria, but resistance to this drug combination has decreased its efficacy and new alternatives are needed. In 2006, the WHO recommended a combination of quinine and clindamycin for treatment of uncomplicated malaria in pregnancy; however, there is a risk of hypoglycemia with quinine use, as well as increasingly drug-resistant P falciparum. Malaria in pregnant women may be more severe than in nonpregnant women and increases the risk for adverse pregnancy outcomes (including spontaneous abortion, stillbirth, prematurity). Malaria infection in pregnant women can be more severe than in nonpregnant women. Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine–pyrimethamine is used to prevent malaria, but resistance to this drug combination has decreased its efficacy and new alternatives are needed. The 2015, World Malaria Report revealed 52% of eligible pregnant women received at least one dose of IPTp-SP and 17% received 3 doses. In all countries where IPTp is recommended, PMI supports strengthening and expanding preventive activities for malaria in pregnancy as part of a partnership between national malaria control, reproductive health, and maternal and child health programs. A pregnant woman has an increased risk (up to four times) of getting malaria and twice the chances of dying from malaria, compared to a non‐pregnant adult, … There is a wealth of evidence showing that the risk of malaria (both infection and clinical disease) is higher in pregnant than in non-pregnant women, possibly due to the immunological, hormonal changes or other factors occurring during pregnancy. If a pregnant woman becomes infected, she should know that many of the antimalarial and antiprotozoal drugs used to treat malaria are safe for use during pregnancy … Malaria is a serious illness, particularly for pregnant women.
A malaria infection is generally characterized by the following signs and symptoms: Fever; Chills; Headache; Nausea and vomiting; Muscle pain and fatigue; Other signs and symptoms may include: Sweating; Chest or abdominal pain; Cough; Some people who have malaria experience cycles of malaria "attacks." While the mechanism is poorly understood, pregnant women have a reduced immune response and therefore less effectively clear malaria infections. Malaria in pregnancy (MiP) is a major public health problem in endemic countries. According to a 2015 Global Call to Action seminar report, ITN use among pregnant women is 38 %. Introduction. Malaria is one of the major causes of preventable death in the world today. Anaemia is common in pregnancy in tropical regions. Most of the available evidence is on Plasmodium falciparum and …
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